Essentiale Forte for dogs: instructions for use, analogues, reviews


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Liver disease can overtake your cat suddenly, bringing great discomfort to the animal and the owner. However, modern medicine is directing all its efforts to cure such serious diseases as cirrhosis and fibrosis of the liver, as well as various forms of hepatitis. For this, veterinarians often prescribe Essentiale for cats. How to use this medicine and how to give it to your pet? Details in this article.

Composition and properties

The manufacturer of the popular medication Essentiale is a Spanish pharmaceutical company. "Essentiale" is sold in the form of a solution for injection, and "Essentiale forte" is sold in the form of capsules for oral administration. The main ingredient in the medicine is soy phospholipids, which are special substances that renew the cell walls of the liver. Additionally, they have the following effects on the cat’s body:

  • help get rid of “bad” cholesterol and intoxicants;
  • restore membrane cells of the liver and ensure the preservation of all the functionality of the organ;
  • improve the transport of useful elements, metabolic processes of proteins and lipids;
  • increase the resistance of the liver organ to the negative effects of toxic components and pharmaceuticals;
  • reduce the liver's need for energy;
  • reduce the number and size of atherosclerotic plaques.

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Essentiale for cats dosage

The pharmaceutical drug "Essentiale" for cats is used for various liver ailments. And, despite the fact that this medication is intended to treat people, it is often prescribed by experienced veterinarians to four-legged patients.

The official instructions for use tell you in detail about the drug, but studying the instructions alone is not enough to start treating your pet.

The selection of effective and safe doses should be done exclusively by a veterinarian, who should be contacted before taking therapeutic measures.

Composition and properties

The manufacturer of the popular medication Essentiale is a Spanish pharmaceutical company.

"Essentiale" is sold in the form of a solution for injection, and "Essentiale forte" is sold in the form of capsules for oral administration.

The main ingredient in the medicine is soy phospholipids, which are special substances that renew the cell walls of the liver. Additionally, they have the following effects on the cat’s body:

  • help get rid of “bad” cholesterol and intoxicants;
  • restore membrane cells of the liver and ensure the preservation of all the functionality of the organ;
  • improve the transport of useful elements, metabolic processes of proteins and lipids;
  • increase the resistance of the liver organ to the negative effects of toxic components and pharmaceuticals;
  • reduce the liver's need for energy;
  • reduce the number and size of atherosclerotic plaques.

When is it prescribed?

For cats and female cats, Essentiale is indicated for use in the presence of the following pathological conditions:

  • exacerbation and chronic forms of hepatitis;
  • cirrhosis of the liver;
  • impaired functioning of the largest digestive gland;
  • death of liver parenchyma cells;
  • diabetes mellitus with liver organ dystrophy;
  • toxicosis;
  • psoriasis;
  • the period after surgery.

The drug "Essentiale" is a low-toxic drug that is highly effective and excellent tolerability.

But according to numerous studies that studied the effects of soy phospholipids on the body of cats, Essentiale should not be used by pets with personal intolerance to any component of its composition.

It will not be beneficial, but will only harm the medicine if given to pregnant females, since the structure includes benzyl alcohol.

Instructions for use

Before using “Essentiale” for cats, you need to show your four-legged pet to a veterinarian, who will make a diagnosis and prescribe an individual therapeutic regimen.

The medicine can be prescribed intravenously or orally depending on the severity of the disease. Typically, the solution is administered 1-2 times a day for 3 weeks, and capsules are drunk twice or thrice a day for about a month.

The dosage is selected by the veterinarian depending on the pet’s body weight and usually for each kg of the cat there is 0.2-0.5 ml of solution or ¼-1 capsule for a fluffy weighing less than 15 kg and 1-2 capsules. for large purrs.

Negative phenomena

If you give Essentiale to a cat in compliance with all the recommendations of a veterinary specialist, then the treatment will only be positive and will not entail negative effects. Otherwise, while taking the hepatoprotector, cats may develop the following side symptoms:

The animal's reaction to drug therapy may be itching.

  • frequent loose stools;
  • urge to vomit, nausea;
  • itching;
  • bitterness in the mouth;
  • bloating and increased gas formation;
  • discomfort in the stomach.

If you observe a negative reaction to the drug “Essentiale” in a cat, you must urgently show your pet to a doctor, since intoxication may occur in the body, requiring disinfection measures. The doctor will bring the animal’s condition back to normal and determine the advisability of further taking the medication or adjust the therapeutic regimen.

special instructions

When using Essentiale in the form of a solution, it is important to know that electrolytes are not suitable for its dilution. Only a clear solution is allowed to be administered to the cat. Before giving your cat a hepatoprotector, you should make sure that it is not expired, and its shelf life is 3 years from the release date indicated on the package.

In order for Essentiale to retain all its medicinal properties until the end of the storage period, it is necessary to create optimal conditions for it, and for this, the tablets and solution are placed in a dark, dry place where the air temperature is between 2-8 degrees Celsius. Small children and animals should not have access to the medicine.

Liver disease can overtake your cat suddenly, bringing great discomfort to the animal and the owner.

However, modern medicine is directing all its efforts to cure such serious diseases as cirrhosis and fibrosis of the liver, as well as various forms of hepatitis. For this, veterinarians often prescribe Essentiale for cats.

How to use this medicine and how to give it to your pet? Details in this article.

Source: https://za-dolgoletie.ru/info/jessenciale-dlja-koshek-dozirovka/

When is it prescribed?

For cats and female cats, Essentiale is indicated for use in the presence of the following pathological conditions:

  • exacerbation and chronic forms of hepatitis;
  • cirrhosis of the liver;
  • impaired functioning of the largest digestive gland;
  • death of liver parenchyma cells;
  • diabetes mellitus with liver organ dystrophy;
  • toxicosis;
  • psoriasis;
  • the period after surgery.

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Who will it harm?

The drug "Essentiale" is a low-toxic drug that is highly effective and excellent tolerability. But according to numerous studies that studied the effects of soy phospholipids on the body of cats, Essentiale should not be used by pets with personal intolerance to any component of its composition. It will not be beneficial, but will only harm the medicine if given to pregnant females, since the structure includes benzyl alcohol.

Instructions for use

Before using “Essentiale” for cats, you need to show your four-legged pet to a veterinarian, who will make a diagnosis and prescribe an individual therapeutic regimen. The medicine can be prescribed intravenously or orally depending on the severity of the disease. Typically, the solution is administered 1-2 times a day for 3 weeks, and capsules are drunk twice or thrice a day for about a month.

The dosage is selected by the veterinarian depending on the pet’s body weight and usually for each kg of the cat there is 0.2-0.5 ml of solution or ¼-1 capsule for a fluffy weighing less than 15 kg and 1-2 capsules. for large purrs.

Negative phenomena

If you give Essentiale to a cat in compliance with all the recommendations of a veterinary specialist, then the treatment will only be positive and will not entail negative effects. Otherwise, while taking the hepatoprotector, cats may develop the following side symptoms:

The animal's reaction to drug therapy may be itching.

  • frequent loose stools;
  • urge to vomit, nausea;
  • itching;
  • bitterness in the mouth;
  • bloating and increased gas formation;
  • discomfort in the stomach.

If you observe a negative reaction to the drug “Essentiale” in a cat, you must urgently show your pet to a doctor, since intoxication may occur in the body, requiring disinfection measures. The doctor will bring the animal’s condition back to normal and determine the advisability of further taking the medication or adjust the therapeutic regimen.

special instructions

When using Essentiale in the form of a solution, it is important to know that electrolytes are not suitable for its dilution. Only a clear solution is allowed to be administered to the cat. Before giving your cat a hepatoprotector, you should make sure that it is not expired, and its shelf life is 3 years from the release date indicated on the package. In order for Essentiale to retain all its medicinal properties until the end of the storage period, it is necessary to create optimal conditions for it, and for this, the tablets and solution are placed in a dark, dry place where the air temperature is between 2-8 degrees Celsius. Small children and animals should not have access to the medicine.

Liver disease can overtake your cat suddenly, bringing great discomfort to the animal and the owner. However, modern medicine is directing all its efforts to cure such serious diseases as cirrhosis and fibrosis of the liver, as well as various forms of hepatitis. For this, veterinarians often prescribe Essentiale for cats. How to use this medicine and how to give it to your pet? Details in this article.

Instructions for use of Essentiale for cats

Liver disease can overtake your cat suddenly, bringing great discomfort to the animal and the owner.
However, modern medicine is directing all its efforts to cure such serious diseases as cirrhosis and fibrosis of the liver, as well as various forms of hepatitis. For this, veterinarians often prescribe Essentiale for cats.

How to use this medicine and how to give it to your pet? Details in this article.

Composition of the drug

The main active ingredient of Essentiale is soy phospholipids - these are special substances that help rebuild the cell wall of the liver, because with cirrhosis, liver cells are severely destroyed.

Further, the work of enzymes that help remove harmful substances from the cat’s body is disrupted, and the ability to restore, so-called regeneration, of cell membranes is also reduced.

In addition, such essential phospholipids help get rid of cholesterol and have a general healing effect, relieving your pet’s body of intoxication.

© shutterstock

Release form

The drug "Essentiale Forte" is produced in two variations:

  • Injections. The package contains five ampoules containing 5 ml of intravenous solution. The total mass of active substances (phospholipids) is 250 mg.
  • Capsules. The package contains one blister with 6 light yellow capsules. The total mass of active substances in this release form is 300 mg.

Essentiale Forte can be given to cats only after consultation with a veterinarian, who will make the correct diagnosis and prescribe the required dosage.

The shelf life of Essentiale is three years from the production date indicated on the packaging. The drug should be stored at a temperature of 2 to 8 degrees Celsius.

Indications for use

You can give Essentiale Forte to your cat for the following diagnoses::

  • cirrhosis of the liver;
  • acute attack of hepatitis or its chronic forms;
  • necrosis (death) of liver hepatocytes (building substances);
  • “congestive liver” syndrome;
  • any liver dysfunction;
  • diabetes mellitus, which develops liver dystrophy;
  • toxicosis (in cases where the cat is pregnant);
  • postoperative therapy;
  • psoriasis.

The only contraindication is an allergic reaction to the components of Essentiale Forte. Can a cat be given Essentiale during pregnancy? Veterinarians do not prescribe the medicine to cats during this period, since the composition contains benzyl alcohol.

© shutterstock

Directions for use and dosage

Cats and cats are prescribed the drug intravenously (using injections) and orally (by mouth, diluted with plenty of water).

In the first method of treatment, the owner or veterinarian administers the injection intramuscularly. The solution can be diluted with autologous blood - the blood of the sick cat itself. This method is performed exclusively in laboratory conditions.

At home, you need to use a dextrose solution, which is purchased in regular or veterinary pharmacies. Salt solutions cannot be used when injecting Essentiale.

The dose is prescribed by the doctor during diagnosis, but, as a rule, it is calculated based on the animal’s body weight.

Calculation: one dose of the drug 0.2-0.5 ml = 1 kg of body weight of a cat. Then the dosage is increased with each kilogram. In the case of capsules, use ¼ capsule - 1 capsule for cats up to 15 kg. Those who weigh more and are quite large animals are prescribed 1-2 capsules.

The regimen for using injections and capsules depends on the severity of the disease - solutions are administered 1-2 times a day for 2-3 weeks , and capsules are taken 2-3 times a day for a period of 2 weeks to a month.

© shutterstock

Side effects

As a rule, there are no side effects when using Essentiale Forte in cats. However, in some cases, the following symptoms may appear:

  • Diarrhea.
  • Nausea and vomiting.
  • Bitterness in the mouth (the cat drinks a lot of water and often sticks out its tongue).
  • Itching.
  • Flatulence or any other stomach discomfort.

At the first sign of these symptoms, you should contact a veterinarian, since it is possible that a slight intoxication occurs in the cat’s body with substances of the drug, the dosage of which turned out to be more than required.

Thus, a cat should be given Essentiale only after consultation with a specialist and a correct diagnosis. “Essentiale” copes well with many liver diseases, and also successfully defeats hepatitis and gallbladder dysfunction, helping to remove all harmful substances from your pet’s body.

Source: https://KoshkaMurka.ru/8713-essentsiale-dlya-koshek.html

Composition of the drug

The main active ingredient of Essentiale is soy phospholipids - these are special substances that help rebuild the cell wall of the liver, because with cirrhosis, liver cells are severely destroyed. Further, the work of enzymes that help remove harmful substances from the cat’s body is disrupted, and the ability to restore, so-called regeneration, of cell membranes is also reduced. In addition, such essential phospholipids help get rid of cholesterol and have a general healing effect, relieving your pet’s body of intoxication.

Release form

The drug "Essentiale Forte" is produced in two variations:

  • Injections. The package contains five ampoules containing 5 ml of intravenous solution. The total mass of active substances (phospholipids) is 250 mg.
  • Capsules. The package contains one blister with 6 light yellow capsules. The total mass of active substances in this release form is 300 mg.

Essentiale Forte can be given to cats only after consultation with a veterinarian, who will make the correct diagnosis and prescribe the required dosage.

The shelf life of Essentiale is three years from the production date indicated on the packaging. The drug should be stored at a temperature of 2 to 8 degrees Celsius.

Directions for use

Hepatovet suspension is intended for oral use. It can be stored for 2 years at a temperature of 2 to 25 degrees, after opening - no more than 3 weeks.

When treating with the drug, the following rules of administration are established:

  • Shake the suspension thoroughly for 1-2 minutes before use.
  • The drug is taken orally by combining it with a small volume of food or using a dispenser syringe included with the drug. It is preferable to squeeze the product onto the root of the animal’s tongue or into the cheek area, this speeds up swallowing and reduces taste sensitivity.
  • The frequency of use per day is 2-3 times.
  • If you miss a medication, you do not need to double the dose; you should take it in the prescribed dosage according to the standard regimen.
  • Duration of therapy is 3-5 weeks. Repeat treatment - after 2-3 weeks.
  • The dosage of Hepatovet is determined individually, based on the weight of the cat. With a large mass, the frequency of administration can be increased.

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Animal weight, kilogramSingle dosage, millilitersPermissible dosage per day, milliliters
until 31No more than 3
3-62No more than 6
From 7 or more3No more than 9

When answering the question, is it possible​ ​Hepatovet​ ​for kittens, the answer is positive, provided that the dose is observed (no more than 2-3 milliliters per day). The drug is also approved for use by pregnant cats, as it does not have a teratogenic effect on the fetus. It is compatible with feed and additives, and other medications.

Indications for use

You can give Essentiale Forte to your cat for the following diagnoses::

  • cirrhosis of the liver;
  • acute attack of hepatitis or its chronic forms;
  • necrosis (death) of liver hepatocytes (building substances);
  • “congestive liver” syndrome;
  • any liver dysfunction;
  • diabetes mellitus, which develops liver dystrophy;
  • toxicosis (in cases where the cat is pregnant);
  • postoperative therapy;
  • psoriasis.

The only contraindication is an allergic reaction to the components of Essentiale Forte. Can a cat be given Essentiale during pregnancy? Veterinarians do not prescribe the medicine to cats during this period, since the composition contains benzyl alcohol.

Directions for use and dosage

Cats and cats are prescribed the drug intravenously (using injections) and orally (by mouth, diluted with plenty of water).

In the first method of treatment, the owner or veterinarian administers the injection intramuscularly. The solution can be diluted with autologous blood - the blood of the sick cat itself. This method is performed exclusively in laboratory conditions.

At home, you need to use a dextrose solution, which is purchased in regular or veterinary pharmacies. Salt solutions cannot be used when injecting Essentiale.

The dose is prescribed by the doctor during diagnosis, but, as a rule, it is calculated based on the animal’s body weight.

Calculation: one dose of the drug 0.2-0.5 ml = 1 kg of body weight of a cat. Then the dosage is increased with each kilogram. In the case of capsules, use ¼ capsule - 1 capsule for cats up to 15 kg. Those who weigh more and are quite large animals are prescribed 1-2 capsules.

The regimen for using injections and capsules depends on the severity of the disease - solutions are administered 1-2 times a day for 2-3 weeks , and capsules are taken 2-3 times a day for a period of 2 weeks to a month.

Essentiale for cats – instructions for use, dosage – Website about pets

Essentiale for dogs is a drug that protects liver cells from destruction and promotes their regeneration. Prescribed for pets with hepatitis of various etiologies and cirrhosis. It has long established itself as one of the best hepatoprotectors. They began to use it in “human” medicine, and only then did it come to veterinary medicine.

What is

Essentiale is a complex of phospholipids obtained from soybeans. Available in injection form and in capsules, which have slightly different compositions.

In addition to phospholipids, the solution contains deoxycholic acid and riboflavin, which also have a hepatoprotective effect. Benzyl alcohol and sodium hydrochloride are included as excipients.

The capsules contain castor oil, solid fats, and extracts obtained from soybeans. These substances regulate stool and cleanse the dog's intestines of toxins, which is very important for liver diseases.

Those that are included in essentiale are completely identical in the structural features of a dog’s liver.

They exhibit greater biological activity than conventional endogenous substances, as they contain many polyunsaturated fatty acids. They are embedded in the membrane of liver cells, preventing their destruction and stimulating regeneration.

As a result, the level of enzymes in the blood decreases, the liver begins to cope with its tasks, and the dog feels good. The drug improves the detoxification function of the liver, the process of protein and urea synthesis in this organ.

Due to the regeneration of hepatocytes, fibrotic changes in the liver are reduced. This prevents the development of cirrhosis in dogs.

The components of Essentiale Forte help normalize the condition of bile and prevent the formation of stones. They also affect the overall metabolism in the body.

When is the medicine prescribed?

  • Acute and chronic hepatitis
  • Toxin damage
  • Cirrhosis
  • Fatty organ degeneration
  • Changes in the liver associated with heart pathology in old dogs
  • Prevention of lesions during treatment with toxic drugs (anti-inflammatory drugs, long-term antibiotic therapy, chemotherapy, recovery after surgery).

Side effects from the use of Essentiale are rare. Some dogs may be allergic to the components of the medication, rash, or itchy skin. Sometimes gastrointestinal disorders are observed - vomiting, diarrhea, loss of appetite.

What are the contraindications to the use of the medicine? It is not allowed for pregnant or lactating dogs, puppies under two weeks of age.

How to give

Prescribe medication according to the dog's weight. Dosage – 0.2-0.5 ml/kg. The drug is administered intravenously for 5-10 days, once a day. If the situation with the dog is very difficult, you can do it twice.

Diluted in glucose or dextrose. Saline solutions are not used for dilution. Then they switch to taking capsules.

They are prescribed 2-3 times a day. Dose for small dogs – ¼, medium – ½, large – 1-2. The course of treatment is from two to four weeks. Can the medicine be given longer?

Since it has few side effects, longer courses are also used. The maximum period for taking Essentiale is 6 months. But the decision to continue therapy must be made by the veterinarian.

In addition, it is recommended to take breaks between courses so that the liver activates its own reserves and regeneration processes. How much does Essentiale cost and where can you buy it?

The drug is sold in both veterinary and regular pharmacies. It is very popular, so finding it will not be a problem. Injections, 5 pieces per package, cost approximately a thousand.

Capsules of 30 cost about 600-700 rubles, 100 - around 2000. The difference in price can be from 100 to 300 rubles per pack.

Source:

Side effects

As a rule, there are no side effects when using Essentiale Forte in cats. However, in some cases, the following symptoms may appear:

  • Diarrhea.
  • Nausea and vomiting.
  • Bitterness in the mouth (the cat drinks a lot of water and often sticks out its tongue).
  • Itching.
  • Flatulence or any other stomach discomfort.

At the first sign of these symptoms, you should contact a veterinarian, since it is possible that a slight intoxication occurs in the cat’s body with substances of the drug, the dosage of which turned out to be more than required.

Thus, a cat should be given Essentiale only after consultation with a specialist and a correct diagnosis. “Essentiale” copes well with many liver diseases, and also successfully defeats hepatitis and gallbladder dysfunction, helping to remove all harmful substances from your pet’s body.

Brief characteristics of the drug

  • Drug name: Essentiale N
  • Name in Latin: Essentiale N
  • Active ingredient: soy essential phospholipids
  • Pharmacological group: hepatoprotector, cytoprotector
  • Object of application: humans, dogs, cats and other mammals
  • Where to buy: medical pharmacies
  • Release form: solution for intravenous injection in ampoules of 5 ml (250.00 mg of 3-sn-phosphatidyl choline), capsules of 300 mg
  • Physical properties: yellow solution, transparent, easily foams; bright yellow, almost brown powder

Release form

are available :

  1. Injection form. Solution for intravenous injection in ampoules of 5 ml. Contains the active substance: essential phospholipids, which are phosphatidylcholine isolated from soybeans, a dried extract that consists of 93% 3-sn-phosphatidylcholine in a dose of 250 mg. There are also excipients: deoxycholic acid - 126.5 mg; sodium chloride - 12 mg; benzyl alcohol - 45 mg; riboflavin - 0.5 mg; sodium hydroxide - 13.4 mg; water - up to 5 ml.
  2. Capsules containing as an active ingredient: essential phospholipids, which are phosphatidylcholine isolated from soybeans, which contains 76% 3-sn-phosphatidylcholine in a dose of 300 mg. Excipients: soybean oil - 36.0 mg; solid fat - 57 mg; castor oil - 1.6 mg; ethyl vanillin - 1.5 mg; ethyl alcohol 96% - 8.1 mg; alpha tocopherol - 0.75 mg; 4-methoxyacetophenone - 0.8 mg. The capsule contains: gelatin - 67.945 mg; titanium dioxide - 0.83 mg; water - 11.495 mg; iron oxide black (dye) - 0.332 mg; iron oxide yellow (dye) - 2.075 mg; sodium lauryl sulfate - 0.125 mg; iron oxide red (dye) - 0.198 mg.

Composition and release form

The drug Hepatovet is used in veterinary medicine for the treatment and prevention of liver pathologies of various etiologies.
It contains phospholipids, flavonoids, amino acids, which have a beneficial effect on the structure of the organ and have the ability to restore it. The advantage of the dosage form of the drug is noted. Since taking tablets for cats causes some difficulties, Hepatovet is presented in the form of a suspension, which facilitates the process of treating your pet.

1 milliliter of product contains:

  • essential phospholipids - 60 milligrams;
  • methionine (essential amino acid) - 100 milligrams;
  • L-ornithine (essential amino acid) - 50 milligrams;
  • milk thistle extract - 15 milligrams;
  • immortelle herb extract - 15 milligrams;
  • auxiliary components.

In terms of its chemical composition and action, the suspension for cats Hepatovet is a low-hazard product (hazard class 4 according to GOST 12.1.007-76).

The drug has a specific aroma and taste, it does not have teratogenic, carcinogenic, or sensitizing qualities.

"Essential" is a vitamin and mineral preparation that contains omega fatty acids.

Essential contains many different oils that restore the cat's fur and skin.

The basis of the drug is exclusively natural plant components (mainly oils):

  • hemp;
  • clove;
  • camphor;
  • tea tree;
  • nima;
  • wintergreens;
  • lavender;
  • oregano;
  • turmeric longa;
  • rosemary;
  • cedar;
  • mint.

Available in pipettes, in cardboard packages on which it is written “Essential 6 spot-on”.

Two forms of the medicinal substance "Essenzale N" are available:

  1. Injection form. Solution for intravenous injection in ampoules of 5 ml. Contains the active substance: essential phospholipids, which are phosphatidylcholine isolated from soybeans, a dried extract that consists of 93% 3-sn-phosphatidylcholine in a dose of 250 mg. There are also excipients: deoxycholic acid - 126.5 mg; sodium chloride - 12 mg; benzyl alcohol - 45 mg; riboflavin - 0.5 mg; sodium hydroxide - 13.4 mg; water - up to 5 ml.
  2. Capsules containing as an active ingredient: essential phospholipids, which are phosphatidylcholine isolated from soybeans, which contains 76% 3-sn-phosphatidylcholine in a dose of 300 mg. Excipients: soybean oil - 36.0 mg; solid fat - 57 mg; castor oil - 1.6 mg; ethyl vanillin - 1.5 mg; ethyl alcohol 96% - 8.1 mg; alpha tocopherol - 0.75 mg; 4-methoxyacetophenone - 0.8 mg. The capsule contains: gelatin - 67.945 mg; titanium dioxide - 0.83 mg; water - 11.495 mg; iron oxide black (dye) - 0.332 mg; iron oxide yellow (dye) - 2.075 mg; sodium lauryl sulfate - 0.125 mg; iron oxide red (dye) - 0.198 mg.

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Pharmacology Essentiale N

Pharmacological effects – hepatoprotective, cytoprotective.

Pharmacodynamics of the drug Essentiale N

Essential phospholipids

represent the main structural elements of the cell wall and membranes of intracellular organelles. In liver pathology, damage to the cell membranes of hepatocytes and their organelles always occurs. This phenomenon is called hepatocyte cytolysis syndrome, which is biochemically manifested by an increase in the activity of alanine and aspartic transaminases in the blood serum. This syndrome causes disruption of the activity of enzymes and receptors, leading to a deterioration in the structural and functional state of hepatocytes. Their ability to regenerate is also reduced.

Phospholipids included in

, are completely consistent in their physicochemical structure with endogenous phospholipids. The activity of essential phospholipids is significantly higher, which can be explained by their higher content of polyunsaturated fatty acids. The above-mentioned high-energy molecules are integrated into defective areas of the membranes of the cell wall of liver cells, which helps restore the integrity of hepatocytes and stimulates their regeneration. The cis-double bonds of the polyunsaturated fatty acids that make up the composition neutralize the parallel arrangement of hydrocarbon chains in the phospholipids of cell membranes, while the structure of the phospholipids of the liver cell membranes “looses,” which leads to an increase in their elasticity and fluidity. Thanks to this, metabolism in hepatocytes significantly improves.

Essential phospholipids, which are the active ingredient of Essentiale, in the body of humans, dogs and cats have a regulating effect on the metabolism of lipoproteins by transporting cholesterol and neutral fats to the sites of their oxidation. This pharmacological effect of essential phospholipids is associated with an increase in the ability of high-density lipoproteins to conjugate with cholesterol.

The cardioprotective properties of Essentiale have been described in humans, dogs and cats.

The drug has a normalizing effect on:

  • on detoxification, urea-synthesizing, protein-synthesizing functions of the liver
  • on the preservation and restoration of phospholipid-dependent enzyme systems and the cell wall of hepatocytes, which inhibits the formation and proliferation of fibrous connective tissue in the liver
  • metabolism of proteins and lipids
  • due to the release of phospholipids into the bile, the lithogenic index is significantly reduced, which leads to the stabilization of bile and the prevention of cholelithiasis

Pharmacokinetics of Essentiale

In the body of humans, dogs and cats, phosphatidylcholine enters hepatocytes, and it is conjugated with high-density lipoproteins.

The half-life of the choline component is about 66 hours, and the polyunsaturated fatty acids are about 32 hours.

Indications for use of the drug Essentiale N

According to the instructions for use of the drug Essentiale in humans, dogs and cats, the following indications are established:

  • liver cirrhosis, acute and chronic hepatitis, hepatocyte necrosis, hepatic precoma and coma, toxic or drug-induced hepatitis
  • cardiohepatic syndrome (cardiac liver fibrosis, congestive liver)
  • hepatocardial syndrome (myocardial dysfunction due to primary hepatic pathology)
  • fatty liver (particularly in diabetes mellitus)
  • toxicosis of pregnancy
  • hepatocyte cytolysis syndrome
  • post- and preoperative therapy, in particular during operations in the area of ​​the liver, gallbladder and ducts
  • radiation syndrome
  • psoriasis

Effect of the drug and indications for use in dogs

The drug has a pronounced effect:

  • improves the antitoxic function of the liver;
  • normalizes metabolic protein and fat processes;
  • protects and activates liver enzyme systems;
  • restores liver cells and inhibits the proliferation of fibrous tissue;
  • stabilizes bile levels and prevents cholelithiasis.


Essentiale forte improves liver function and stabilizes bile levels.
Essentiale Forte is prescribed to dogs for any disorders of the liver: chronic, acute, drug-induced, toxic cirrhosis; hepatitis; fatty liver; pre- and postoperative therapy.

Method of using essentiale in humane medicine and its dose to humans

The drug is used in the form of intravenous injections. It is undesirable to inject this drug intramuscularly, which is due to the development of local reactogenic reactions (the drug irritates soft tissues and causes an inflammatory reaction). The standard dose of Essentiale for humans is 5–10 ml (1–2 ampoules). For severe forms of hepatopathy, use 10–20 ml (2–4 ampoules) per day. The contents of 2 ampoules (10 ml) can be administered intravenously at a time. The drug can be used twice a day. It is strictly forbidden to mix essential phospholipids in the same syringe with other medications. It is recommended to dilute the drug with the patient’s blood in a 1:1 ratio (using autologous blood).

If necessary, the drug is diluted with only a 5-10% glucose solution, and the diluted drug solution should be transparent throughout the entire time of intravenous injection.

It is strictly forbidden to dissolve the drug with electrolyte solutions (isotonic nitride chloride solution, Ringer's solution, etc.).

It is recommended to supplement intravenous administration with oral forms of the drug as quickly as possible.

The drug is also used orally. Capsules of the drug must be swallowed whole and washed down with a sufficient volume of water (about 200 ml).

For adults and adolescents over 12 years of age, take 2 capsules 3 times a day with meals. The duration of use of Essentiale is not limited (determined by the attending physician).

Instructions for use and dosage of the drug

To restore liver function, treatment with the drug is supposed to be used over a long period of time. In severe condition of the animal, oral administration may be complicated by vomiting, therefore, in case of postoperative treatment, hepatic coma, cell necrosis and severe toxic damage, treatment begins with intravenous injections of the drug. Then intravenous administration is supplemented by taking Essentiale Forte N as a course of treatment.

If intravenous administration of the drug is impossible for some reason, then in case of fatty liver degeneration or chronic hepatitis, only the oral form of the drug is prescribed.

Essentiale Forte is given before meals 2-3 times a day. For medium and large dogs, the dosage is 1 capsule per dose. Due to the size of the capsule, administering the medication to small dogs may be difficult. In this case, it is permissible to open the capsule, divide the pasty contents into 2-4 parts and feed it to the animal with water or a small amount of food.


The photo shows the contents of the Essentiale Forte capsule.

The course of treatment, depending on the disease and health indicators, can range from 2 weeks to several months. If necessary, the course of taking the drug is repeated.

Important. Essentiale Forte is recommended for restoring and maintaining liver function in dogs with piroplasmosis, because This disease primarily affects the animal's kidneys and liver. The duration of the course is determined by the attending physician depending on the indicators.

Contraindications and side effects of Essentiale Forte for dogs

The drug has no contraindications, only individual sensitivity is possible.

Side effects to the drug develop very rarely and can manifest themselves in the form of allergies, nausea, soft or loose stools.

Method of application of essential veterinary medicine and its dose for dogs and cats

The drug is used in cats and dogs as intravenous injections. This drug is not injected intramuscularly (the development of local reactogenic reactions is possible). The standard dose of Essentiale for dogs and cats is 0.2-0.5 ml/kg body weight 1 time per day for 5-10 days. For severe forms of hepatopathy in dogs and cats, the drug is used intravenously 2 times a day for 2-3 weeks. The drug is diluted with autologous blood or dextrose solution. Saline solutions are not used to dilute Essentiale.

When using Essentiale for dogs and cats

It is recommended to replace or supplement the injection form of the drug with an oral one as soon as possible.

The drug is also used orally. Cats and cardic dogs use 1/4 capsule of Essentiale, medium breeds - 1/2 - 1 capsule, large and giant breeds - 1-2 capsules of 2-3 rvd for 2-4 weeks.

Contraindications to the use of Essentiale

According to the instructions for use of the drug "Essentiale", a number of contraindications have been established:

  1. allergic reactions
  2. children under three years of age
  3. allergy and hypersensitivity to any of the ingredients of the drug

Use Essentiale with caution during pregnancy

, since the drug contains benzyl alcohol, which penetrates the hematoplacental barrier quite well. Clinical studies have established that the use of drugs containing benzyl alcohol in newborns with a high frequency of developing dyspnea syndrome with a fatal outcome.

Side effects on the drug Essentiale

In humans, dogs and cats, side effects on Essential are extremely rare.

The following side effects are described:

  • allergies (urticaria)
  • delayed type hypersensitivity
  • diarrhea
  • nausea
  • bitter taste in the mouth
  • itching
  • skin rash
  • a soft chair
  • stomach discomfort

special instructions

Only use a clear solution. Foaming may occur when using the drug.

Release form

Ampoules with a solution for intravenous injection, 5 ml each, containing 250 mg of essential phospholipids. Ampoules of 5 ml (dark glass).

Capsules that contain 300 mg of active substance.

Manufacturer

FamarHealthCareServices (Madrid, Spain). Address: Avenida de Leganes, Alcocorn (Madrid), Spain.

Storage conditions for the drug "Essentiale N"

Store out of the reach of children, namely in the refrigerator at a temperature of 2 to 8 °C.

Expiration date of the medicine

According to the instructions for use for humans, dogs and cats, the shelf life is three years.

The drug should not be used after its expiration date.

Instructions for use: dosage, contraindications

How to give Essentiale?
Dogs are given Essentiale Forte three times a day, one capsule for three months. However, in the first week of treatment, it is better to administer the drug intravenously in the form of a solution of one ml per injection. Only from the second week is it better to switch to capsules. They are best given immediately before meals. If necessary, the course of treatment can be repeated or continued. Only in the form of an injection solution, the drug is used for hepatitis, liver cell necrosis, toxic liver damage, hepatic coma, and postoperative treatment.

Only capsules can be given for chronic hepatitis in dogs or fatty liver degeneration. There are no contraindications when using Essentiale Forte.

Side effects of Essentiale Forte for dogs

When taking high doses, gastrointestinal upset in the form of diarrhea may very rarely occur, which disappears when you stop taking the drug or significantly reduce its dosage.

The drug is prescribed with caution to pregnant and lactating bitches, as well as puppies up to 2 months, since the drug contains benzyl alcohol.

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