Instructions for the use of gentamicin in veterinary medicine. Calculate the optimal dose of the drug. Explore the breadth of gentamicin's antibacterial effects in cats. Improve therapy effectiveness by 400%

Gentamicin 4TM

1 General information
1.1 Gentamycin 4% (Gentamycini 4%).

1.2 Active substance gentamicin sulfate. 1 ml of the drug contains 40 mg of gentamicin.

1.3 Solution for injection - is a transparent liquid from colorless to yellow, without visible mechanical inclusions.

1.4 The drug is released in 10.0; 20.0; 50.0; 100.0 and 200 ml in glass bottles. Store the drug according to list B in a dry place, protected from light, at a temperature from plus 5°C to plus 25°C.

The shelf life of the drug is 2 years from the date of manufacture, subject to storage rules.

2 Pharmacological properties

2.1 Gentamicin has a bacteriostatic effect on gram-positive and some gram-negative microorganisms, including E. Coli, Enterobacter spp., Klebsiela spp., Salmonella spp., Shigella spp., Pasteurella multocida, Pseudomonas aeruginosa, Campilobacter, some non-pigmented Serratia species, indole positive and indole negative Proteus spp. The antimicrobial effect of gentamicin is based on the inhibition of peptide bonds during protein synthesis in the ribosomes of the bacterial cell.

2.2 The drug is well absorbed after intramuscular injection, reaching a maximum concentration in the blood an hour after injection, the therapeutic concentration in the body remains for 8 - 12 hours. Gentamicin penetrates into the pleural and abdominal cavities, as well as through the placenta. It is excreted predominantly unchanged through the kidneys.

3 Procedure for using the drug

3.1 The drug is used in large and small cattle, horses, pigs, dogs, cats for the treatment of respiratory and gastrointestinal infections, sepsis, peritonitis, pyelonephritis, arthritis, polyarthritis, dermatitis (in dogs) and other animal diseases caused by microorganisms sensitive to gentamicin .

3.2 The drug is administered intramuscularly twice a day with an interval of 10-12 hours for 3-10 days at the rate of 20-30 mg (or 0.50-0.75 ml) per 10 kg of live weight.

3.3 Gentamicin 4% solution cannot be mixed in the same syringe with other medications.

3.4 Side effects. Allergic reactions are possible in hypersensitive animals.

3.5 Contraindications. Simultaneous or sequential use of gentamicin with other ototoxic and nephrotoxic drugs (streptomycin, kanamycin, neomycin), as well as with diuretics and muscle relaxants is not allowed. The drug should not be used in cases of severe renal impairment.

3.6 Slaughter for meat of farm animals to which the drug was administered is permitted no earlier than 21 days after the last use of the drug. The meat of animals forcedly killed before the established deadline can be used to feed fur-bearing animals or to produce meat and bone meal.

Milk obtained from cows that have been treated with the drug must not be used for food purposes during the treatment period and for 3 days after stopping the use of the drug. This milk can be used to feed animals after heat treatment.

4 PERSONAL PREVENTION MEASURES

4.1 When working with the drug, personal hygiene measures and safety regulations should be observed.

5 PROCEDURE FOR SUBMISSION OF COMPLAINTS

5.1 If the drug does not comply with the requirements specified in this manual, as well as if complications are identified, stop using the drug and report this to the State Institution “Belarusian State Veterinary Center” (Minsk, Krasnaya str., 19-a, tel. 290- 42-75) and to the manufacturer. At the same time, at least 3 unopened packages of the drug from the series that caused the complication are sent to the Belarusian State Veterinary Center.

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special instructions

When working with antibacterial solution, it is important to observe personal hygiene measures and safety regulations. It is strictly forbidden to administer the medicine with a non-sterile syringe or if there are traces of other solutions on its walls. Otherwise, the risk of developing side symptoms, abscesses and other inflammatory reactions increases significantly. The shelf life of Gentamicin is 2 years, after which the use of the antibiotic is strictly contraindicated. The package with ampoules should be stored in a dry place, away from light, where the air temperature does not rise above 25 degrees Celsius. Small children and animals should not have access to the medication.

Sources:

https://koshkamurka.ru/8422-kak-davat-gentamitsin-koshke.html https://kot-i-koshka.ru/antibiotiki-dlya-koshek/ https://infokotiki.ru/medicamenty/antibakterialnye/gentamitsin -dlya-koshek.html

Contraindications

According to the instructions, do not use in dogs with hypersensitivity (allergy) to aminoglycosides. Ineffective against most anaerobic bacteria (those microorganisms that can live without oxygen). Do not use dogs that require acute hearing to perform their job (working breeds, military dogs, police dogs, guide dogs, guard dogs, etc.). Since hearing or vestibular (balance) impairment may be irreversible.

• Do not use gentamicin in dogs with kidney disease, as this group of medications may worsen the disease if present.
• Not for use in pregnant or nursing dogs.
• Not for use in dogs with myasthenia gravis or other neuromuscular disorders.
• Not for use in dogs with fever or dehydration.

Contraindications

Contraindications for Gentamicin mainly relate to the complete incompatibility of the drug with other drugs. Gentamicin is prohibited from being used simultaneously with penicillins, other aminoglycoside antibiotics, some cephalosporins, chloramphenicol, polymyxin, colistin, and sulfonamides. In addition, the following are contraindications:

• Renal dysfunction;
• Hypersensitivity to gentamicin;
• During pregnancy;
• Use with other nephrotoxic and ototoxic drugs;
• Use with some anesthetics (halaton);
• Use with muscle relaxants.

Drug overdose

If you do not adhere to the dosage while using this medication or exceed the time limit for using Gentamicin, then an overdose of this drug may occur. Such poisoning may have a negative impact on your pet's hearing and kidneys. He may also experience an allergic reaction, which will be accompanied by a rash and itching. Problems with the eighth cerebral nerve are also possible.

And most importantly, remember that long-term use of Gentamicin has a very bad effect on the cat’s body. If you use this medication for more than 7 days, severe destructive damage to the kidneys and nervous system may occur. But most often the development of acute renal failure occurs. In most cases, such problems lead to the death of a pet.

How to give Gentamicin to a cat?

Nowadays, antibiotics are becoming increasingly popular in veterinary medicine.
They have become indispensable assistants in the treatment of various diseases. Although it is worth recognizing the fact that most of these drugs cause irreparable harm to the body of four-legged animals. One of these antibiotics is Gentamicin for cats. On the one hand, it destroys harmful bacteria, and on the other, it negatively affects the internal organs of the pet. Still, let's try to figure out what is more good or harmful from Gentamicin? And how should you take this remedy correctly so that you don’t have to deal with a lot of problems related to your cat’s health?

GENTAMICIN SULFATE 4

INJECTION SOLUTION.

"GENTAMICIN SULPHATE 4%" (Gentamycini sulfas 4%). In appearance, the drug is a transparent, colorless or light yellow to yellow liquid without mechanical inclusions. 1.0 ml of the drug contains 0.04 g of gentamicin in the form of gentamicin sulfate and water for injection up to 1.0 ml. The drug is produced in glass bottles with a volume of 50.0; 100.0 and 200.0 ml.

The drug is stored according to list B in a dry place, protected from light, at a temperature from 0 ºС to plus 20 ºС. The shelf life of the drug is 2 years from the date of manufacture, subject to the rules of storage and transportation.

PHARMACOLOGICAL PROPERTIES

Gentamicin, which is part of the drug, is produced by Micromonospora purpurea and belongs to the group of aminoglycoside antibiotics. The drug disrupts protein synthesis by inhibiting peptide bonds during protein synthesis on the ribosomes of the bacterial cell. The drug has a wide spectrum of antimicrobial action, is active against most gram-positive and gram-negative microorganisms, including Proteus spp., Escherichia coli, Salmonella spp., Pseudomonas aeruginosa, Pasteurella spp., Streptococcus spp. and Staphylococcus spp. The drug does not affect anaerobic bacteria, fungi, viruses and protozoa. When administered intramuscularly, the drug penetrates well into many organs and tissues. The maximum concentration in the blood is reached one hour after administration. After a single injection, the therapeutic concentration of the antibiotic in the body remains for 8 to 12 hours after administration. Gentamicin penetrates into the pleural and abdominal cavities, as well as through the placenta. When administered orally, the drug is practically not absorbed from the gastrointestinal tract and exerts its effect within 12 hours. When administered parenterally, gentamicin is excreted from the body unchanged mainly in the urine, and when administered orally in feces.

APPLICATION OF THE DRUG

The drug is used to treat animals with respiratory and gastrointestinal diseases, sepsis, peritonitis, meningitis, pyelonephritis and other diseases caused by antibiotic-sensitive microorganisms. The drug is administered intramuscularly or orally twice a day with an interval of 10–12 hours in the doses indicated in the table:

SIDE EFFECT

When using the drug, allergic reactions (skin rash, itching, fever) may occur. Ototoxic and nephrotoxic effects are possible. If allergic reactions occur, the drug should be discontinued and antihistamines (allervet, diprazine) and calcium supplements (gluconate or chloride) should be prescribed.

CONTRAINDICATIONS

When using the drug, allergic reactions (skin rash, itching, fever) may occur. Ototoxic and nephrotoxic effects are possible. If allergic reactions occur, the drug should be discontinued and antihistamines (allervet, diprazine) and calcium supplements (gluconate or chloride) should be prescribed.

Simultaneous or sequential use of gentamicin with other oto- and nephrotoxic drugs (streptomycin, kanamycin, neomycin) and furasemide is not allowed. The drug should not be used in animals with severe renal impairment.

SPECIAL INSTRUCTIONS

Slaughter of animals for meat is permitted no earlier than 21 days after the last use of the drug. Meat from animals forcedly killed before the expiration of the specified period can be used to feed carnivorous animals. Milk must not be used for food purposes during the treatment period and for 72 hours after stopping the use of the drug. Before this period, milk can be used as animal feed after heat treatment.

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Published in the category For pets (dogs, cats), For cattle, For horses, For small livestock, For pigs, Antimicrobials

Composition and mechanism of operation

An aminoglycoside antibiotic with a broad spectrum of antimicrobial action, Gentamicin, is active against many gram+ and gram- bacteria.

In veterinary medicine, it is used for the treatment of cattle, domestic animals, pigs and horses. In one of the scientific articles published in the journal in 2020, Kukaeva E. Yu. describes the effective treatment of viral infections of cats and the pointlessness of taking antibiotics for their treatment. This is due to the fact that the active component of the medicine does not act against viruses, as well as fungi, anaerobic bacteria and protozoa. “Gentamicin” is sold in the form of a solution, which, through injection, perfectly penetrates into all tissue structures and organs of the cat’s body, reaching its maximum concentration in the blood within 60 minutes after manipulation. The therapeutic effect lasts up to 12 hours.

Medicines for animals Gentamicin sulfate 4 injection solution

Brief description: Gentamicin sulfate 4% is an antibacterial drug belonging to the group of aminoglycosides and having a bactericidal effect. It has a fairly wide spectrum of action and is destructive to most gram-positive pathogens and some gram-negative bacteria (including pathogenic strains of streptococci, staphylococci, Proteus, E. coli and salmonella). However, the drug does not have a negative effect on anaerobic species of microorganisms, protozoa, fungi or viruses. The drug is prescribed to domestic and farm animals for the treatment of respiratory diseases, infections of the gastrointestinal tract and genitourinary system, which are bacterial in origin and whose pathogens are sensitive to gentamicin. According to the degree of toxic effects, the drug belongs to the group of substances moderately hazardous to animals. In high concentrations it can have nephrotoxic and ototoxic effects.

For whom: Gentamicin sulfate 4% can be used to treat domestic animals (cats and dogs), large and small cattle, pigs, horses.

Release form: the drug is a clear liquid without color or with a slight yellowish tint, which is packaged in sterile glass bottles of 5, 10 or 100 ml.

Dosage: Gentamicin sulfate 4% is used only for intramuscular injection or oral use. Injections are given twice a day. The daily dosage for horses, cats and dogs is 0.6 ml for every 10 kg of body weight (this corresponds to 2.5 mg of pure gentamicin per kilogram of body weight). Sheep and cattle are given 0.75 ml of solution per 10 kg of body weight per day, and the oral dosage is 2 ml per 10 kg of body weight. For pigs, the daily dose of the drug for every 10 kg is 1 ml for intramuscular injection and 1.5 ml for oral administration. The maximum volume of solution that can be administered in one injection is 15 ml for large animals, 10 ml for pigs, 5 ml for sheep, and 2.5 ml for dogs or cats.

Limitations: Solution for injection should not be used to treat animals that have previously had hypersensitivity reactions to aminoglycoside antibiotics. It is also not used for therapeutic purposes for pregnant or lactating females and individuals with kidney pathology. Slaughter for meat is permitted no earlier than 21 days after the end of treatment. The milk is ready for consumption after three days.

Veterinary advice

Before any vaccinations, the animal MUST undergo flea and worm treatment!

Rabies is a disease with a 100% fatal outcome. All species of mammals and humans are susceptible to it. Therefore, rabies vaccination is required for all pets.

We invite you to find out what fish are found in Baikal

Don't forget about vaccination. There are a huge number of preventive vaccinations, but we prefer the NOBIVAK Tricat vaccine (live lyophilized vaccine against viral rhinotracheitis, calicivirus infection and feline viral panleukopenia) and NOBIVAK Rabies (against rabies), Holland.

We remind you that vaccine developers recommend the optimal vaccination schedule for each vaccine. If you are not a veterinarian, do not make any adjustments and follow what is written in the instructions or what your veterinarian says. The first vaccinations are given to kittens twice.

Immunity is developed only 14 days after the second vaccination. And keep in mind that during the month and a half that the vaccination schedule is in progress, the kitten’s body weakens.

Immunity decreases, so during this period you need to protect your pet from unnecessary contact with other animals, from possible drafts; do not bathe or wash the animal during this period. Next, the animal must be vaccinated once a year.

WHAT MEDICINES IS IT DESIRABLE TO HAVE IN A CAT'S HOME MEDICINE KIT?

Let's tell you in order. For any parents, the hardest time is when their baby is sick. In this case, the kitten, cat or cat is our child.

We are losing peace and sleep, we are ready to share his illness with the baby, to take it upon ourselves, if it were possible, we are ready to do anything to ensure that our treasure recovers quickly and becomes cheerful and happy again.

The kitten cannot tell where it hurts and how. Only suddenly he gets sick. This is where essential medications come to the rescue.

– in case of cuts, bites, if the wound is not lacerated, treat with 3% HYDROGEN PEROXIDE. In the future, if the wound gets wet, treat it again with peroxide and sprinkle with dry STREPTOCIDE (as an anti-inflammatory disinfectant). If the wound cracks, lubricate it with SYNTHOMYCIN EMULSION. If the wound festers, then the well-known VISHNEVSKY OINTMENT will help us all.

In case of severe fatigue, heat stroke, heart failure, and weakness of breathing, you can give heart medications: Corvalol, Valocordin, etc. It is even better to give an injection of SULPHOCAMPHOCAINE.

For general mild malaise and lethargy, we inject our patients with IMMUNOFAN. It stimulates the body's vital resources and helps it cope with the disease faster.

There is also a drug called BAYPAMUN from Bayer. It is also a nonspecific stimulator of the body's own defenses.

If vomiting appears and the stool suddenly deteriorates, then you need to stop feeding altogether (at least for one day), give plenty of fluids with a weak pale pink solution of POTASIUM MANganese and 1-2 tablets of ACTIVATED CHARCOAL. In addition, rice water and chicken broth diluted with water are very helpful.

We definitely give 1/2 tablet of SULGIN 2 times a day, and if the stool does not improve within 24 hours, then we begin to give stronger and more effective remedies.

Namely antibiotics: chloramphenicol 1/6 tablets 2 times a day and always probiotic agents “BIFICOL” or “BIFIDUM BACTERIN”, or better yet special for animals “LAKTOBIFADOL” or “BIFITRILAC”, and best of all “VETOM 1:1”.

If a day after the first symptoms appear the kitten does not feel better, if there is also vomiting and it does not stop, then there is only one piece of advice - immediately contact a veterinarian.

This can be very life-threatening poisoning, hepatitis, feline enteritis (panleukopenia), etc. The main thing here is not to be late.

Another problem, constipation, is also unpleasant. In this case, gentle laxatives are needed. This can be milk, vegetable oil (a teaspoon), and a very effective remedy is Vaseline oil (a tablespoon).

Deworming is a very necessary thing for our pets. If there are children in families, this is a must.

Once a quarter we give a kitten, a cat or a cat antihelminthic drugs, we ourselves always use only DRONTAL for cats, 1 tablet per 4 kg of weight, Bayer. The drug contains praziquantel and pyrantel embonate, so it kills both roundworms and tapeworms.

Even a five-fold overdose of Drontal is tolerated by cats without symptoms of poisoning. It is MANDATORY that before worming, you must undergo flea prevention!

Since fleas are carriers of many infections, eggs and larvae of worms. We use a drug such as “Advantage” (drops) from Bayer.

This wonderful drug is good because it is not absorbed into the blood, spreads over the skin and kills up to 98% of all fleas, their larvae and eggs within 12 hours. And the best thing is that this drug can be used for pregnant and lactating cats; it does not affect pregnancy.

In addition, the drug has an umbrella effect, that is, if the mother cat is treated, then baby kittens up to 8 weeks of age also do not become infected with fleas. An analogue may be the drug "Frontline"

Now Russian developers produce many domestic drugs, which also help us, animal owners, a lot. The drug FOSPRENIL is a very effective remedy for the prevention and treatment of viral infections in cats and dogs.

And, of course, the main thing is proper balanced nutrition.

It is always advisable to have the necessary set of medications and tools at home or take it with you if you take your cat with you on a trip.

Instruments and dressings:

1. Sterile bandages (wide and narrow)
2. Absorbent cotton wool
3. Rubber tourniquet
4. Scissors with rounded ends
5. Disposable syringes 1.0; 2.0; 5.0; 10.0; ml
6. Tweezers
7. Blunt tip pipette
8. Blanket (made from thick stocking) with slits for paws
9. Syringe for newborns
10. Sterile wipes
11. Medical thermometer
12. Nail trimmers
13. Fixing bag (the cat is placed there, leaving only the head outside, the bag is tied with a ribbon) It is needed when the cat needs to clean its ears, give it a pill, transport it, etc.

Vitamin preparations:

1. Ascorbic acid ampoules (vitamin C)
2. Vitamin B12
3. Vitamin D3
4. Vikasol (etamsylate) (vitamin K) in ampoules or tablets
5. Microvitam (complex preparation)
6. Aminovit (complex preparation)
7. Glucose in ampoules (usually 40% solution)

Antihistamines (anti-allergenic):

1. Diphenhydramine (amp or tablet)
2. Suprastitis
3. Tavegil

Antiseptics and disinfectants:

1. Alcohol 70% or vodka
2. Hydrogen peroxide 3%
3. Boric acid solution, 3%
4. Zelenka
5. Iodinol
6. Iodez
7. Potassium permanganate (potassium permanganate)
8. Lugol's solution
9. Furacilin in the table. 10 pieces (diluted in hot water at the rate of 1 tablet per glass of water. Stored for a long time in a cool place)

Adsorbents:

1. Activated carbon(table)
2. Polyphepan (powder)

Antiemetics

Anthelmintics

1. Drontal (1 tablet/4 kg weight)
2. Praziquanlet
3. Kanikquantel plus (1 tablet/10 kg weight)

Painkillers and remedies

1. Novocaine in amp. (0.5% or 2% solution)

Antimicrobial agents:

1. Streptocide tablets (antimicrobial drug) for local use
2. “Zooderm” drops – antimicrobial, antihistamine and anti-inflammatory agent (for otitis, dermatitis, poorly healing wounds and other skin diseases)

Anti-inflammatory drugs (homeopathy):

1. Traumeel (Anti-inflammatory, antiexudative, immunostimulating)

Ointments and oils:

1. Vaseline oil
2. Synthomycin ointment (synthomycin liniment) – antibacterial ointment

Antibiotics

1. Gentamicin 4% in ampoules
2. Ampicillin (ampiox) ampoules or tablets.
3. Levomycetin tablets
4. Tetracycline hydrochloride
5. Baytril (broad spectrum, especially for animals)
6. Biseptol 120 (combined antibacterial drug with a wide spectrum of bactericidal action) is used in the treatment of various infections.

– Immunostimulants

1. Baypamun (a nonspecific stimulator of the body’s own defenses. It is an effective prevention of the effects of stress caused by transportation, exhibition, and hospital stay)
2. Immunofan (stimulates the body's defenses), has antiviral and antibacterial effects (also used to increase reproductive function)

– Immunomodulators:

1. Ribotan (stimulates the body's defenses, helps prevent and increase the effectiveness of therapy for plague, viral enteritis, hepatitis, influenza, demodicosis, etc.)
2. Maxidin (immunomodulator and broad-spectrum anti-inflammatory drug)* When used with Fosprenil, a twofold reduction in dosage is possible.
3. Fosprenil
4. Gamavit

We suggest you familiarize yourself with Burns in cats and kittens

Eye products:

1. Lakrimin eye drops – aniseptic
2. Lakrikan (eye drops) - aniseptic - provides an animicrobial, local anesthetic agent
3. Levomycetin 0.25% (eye drops) (broad-spectrum antibiotic)
4. Taufon (eye drops)
5. Visine (relieve eye inflammation)
6. Hydrocortisone or tetracycline eye ointment (anti-inflammatory, antipruritic and decongestant drug)
7. Iris (eye drops)
8. Ciprovet (eye drops) (anti-inflammatory antimicrobial drug)
9. Anandin (ophthalmic-intranasal) (anti-inflammatory, antimicrobial and regenerating effect)

Gentamicin instructions for use injections for animals

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Release form and method of use

Available in the form of an injection solution. The liquid should be colorless, but a slightly yellowish tint is allowed. Under no circumstances should a solution be used to treat animals if it contains at least a minimal amount of impurities or the presence of sediment is observed! The medicine is packaged in 2/5/10 ml ampoules and 50 ml dark glass bottles (there are other variations, it all depends on the manufacturer). One milliliter of solution contains 40 mg of active substance.

It is administered intramuscularly only. The product is characterized by good absorption in the body, the maximum concentration in blood plasma and other biological fluids is achieved in just an hour. This content of the drug components remains in the animal’s body for 10-12 hours. A positive feature of gentamicin is its penetration into the pleural and abdominal cavity, which makes it possible to use the drug for the treatment of pleurisy and peritonitis (caused by gram-negative microorganisms, of course). A negative feature is that it penetrates the placental barrier just as easily, so you should not use the medicine to treat pregnant cats.

As we have already said, the drug should be administered exclusively intramuscularly, paying special attention to the rules of asepsis. What is the dosage of gentamicin for cats? On the first day, administer at a dose of 1.1 ml for every 10 kg of live weight per day

Frequency of application – twice a day. Since there are few such giants among cats, it is better to administer the medicine at the rate of 4.4 mg of active substance per kilogram of live weight. As in the previous case, the drug should be used twice a day.

Instructions for use

The course of treatment for a pet lasts up to 5 days through injection of the drug.
The method of use and dosage is determined by the veterinarian personally for each cat, after its examination and diagnosis. “Gentamicin” in the form of a solution is usually prescribed to purrs at 1.1 ml per 10 kg of pet’s weight every 12 hours. Then the cat is given an injection at the same dosage once a day until complete recovery. This often takes up to 5 days. It is better for a newborn kitten to abstain from this antibiotic, but if this is not possible, then the adult dose will need to be reduced by exactly 2 times.

Classification of antibiotics. Release forms

You shouldn’t try to remember all the possible commercial names of drugs that cats can use. It is always enough to ask which antibiotic or active substance is included in the antimicrobial drug.

Cat owners must learn the most important rule - only a veterinarian can select antibiotics! Not everyone can inject a cat with antibiotics, because... Not all antibiotics are acceptable for use in cats, not all have analogues in human medicine and can be replaced with some other drug.

If the doctor has no doubt about the diagnosis, then it is best to focus on narrowly acting drugs. If the condition is complicated by secondary infections or there is no time to isolate the pathogen, a broad-spectrum antibiotic certainly comes to the rescue.

Doses of antibiotics are prescribed only by a specialist, based on the specific case of the disease. All information provided is for informational purposes only!

Penicillins

prescribed for purulent wounds, burns and various types of inflammation of dermal origin (bacterial skin pathologies). In some cases, they are prescribed for pathologies of the urinary system.

Cephalosporins

broad-spectrum antibiotics, divided into several generations according to their origin and characteristics of action. Suitable for almost any infection, when there is no time to wait for a bacterial sensitivity test or when therapeutic measures need to be applied as soon as possible. Infections of the gastrointestinal tract, genitourinary system, breathing and sometimes vision can be treated. Therapy for sepsis responds well.

Aminoglycosides

They cope well with colds, the onset of peritonitis, and pneumonia. May help with soft tissue infections. A very toxic group, prescribed in particularly difficult cases.

Killed a cat

ru_vetdmartynov Friends! The cat had an eye injury, the veterinarian prescribed: 1. Oframax w/m.2. Gentamicin intramuscularly.3. Tetracycline externally.4. Levomycetin externally.5. Furacilin externally. At first everything was fine, he came to life, began to eat well, his eye opened. After 2 weeks, oframax and tetracycline were stopped, from the excess of which the conjunctiva began to swell.

Gentamicin was left in place for at least 24 days. Every 3 days I took the cat for a checkup.

But the cat didn’t make it to 24 days. Today the cat suddenly became ill: he moans continuously, draws in his sides, breathes deeply, his hind legs give out. He tries to get up, but falls. As soon as I noticed this, I took him to another 24-hour clinic (ours is not open at night).

The veterinarian was horrified when he found out what dosage of gentamicin we injected the cat with. And we injected as our veterinarian prescribed - 0.7 ml twice a day for 18 days (and we still need to inject for 5 days), this turns out to be 56 mg per day - 5-10 times higher than the maximum dose!!! They dripped as much as they could, left the catheter, and told me not to go to that clinic again, but to go straight to them in the morning.

The assumption is certain - they killed the kidneys. Is it still possible to save the cat or not? He lies there moaning and wheezing...

How else can I explain to my five-year-old son what happened to my beloved cat?..UPD1: the cat died. Before death, the legs were completely paralyzed (first the hind legs, then the front ones), shallow breathing 40/min, convulsive, retraction of the sides, with whistling and wheezing, the tongue was bitten, he tried to get up, but could not, he screamed protractedly, although he had never meowed in his life. Rectal temperature 36 degrees.

The last screams were already gurgling (renal failure - {amp}gt; heart failure - {amp}gt; pulmonary edema, paralysis of the respiratory muscles - the correct chain of events?). The prescription from the clinic says: “Gentamicin 0.7 ml 2 times a day “The maximum daily dose, according to various sources, is 0.5 mg per 10 kg for cats, up to 7 mg/kg for humans for 10 days. The cat’s weight is 2.5 kg, age 5 years.

In any case, the dose of 58 mg/day that the cat received was an order of magnitude higher, plus an overestimation of the period by 2-3 times. The cat had no chance to survive. Clinic: “Noah’s Ark”, Krasnodar, st. Chekistov, 1.

UPD2: Today, a week later, the attending physician (who is also the director of the Noah's Ark clinic, pictured below) Vetoshkin Alexander Viktorovich returned from vacation, went to work and I visited him at the clinic.

It turns out that the clinic had already read my review, so they invited me behind a closed door. I showed the cat’s veterinary passport with a photo, then the treatment manual (see scan above) and asked to find the mistake. “I don’t see anything, except that the dose of gentamicin is a little too high... We always overdo the dose because there are no blood vessels in the vitreous.”

To the question “How will you apologize, doctor, to me and my family?” received the answer “For what? You see, I didn’t see why he died.” Naturally, you were on vacation, you were not in Russia! But you see the treatment guidelines prescribed by your clinic, right? 56 mg for 18 days - you still don’t see why the cat died?

I have a video, can I show you the agony? In short, Alexander Viktorovich Vetoshkin, in my presence, went into a deep denial of involvement and responsibility. I left him my bank details with the cost of the animal plus the cost of treatment. I think that any decent person would apologize and compensate for this minimum, and the family would forgive the emotional bitterness of the absurd loss. And the reputation of an HONEST doctor would be saved.

Alexander Viktorovich! A true professional is CAPABLE of admitting his mistake (we are all human) and is READY to take responsibility. Everyone has already looked, everyone has found a mistake, except you. Don’t dig a hole in your reputation and the reputation of your Noah’s Ark clinic. Admit your mistake if you are a professional, and we will “rehabilitate” you.

ru_vetlazy_otter Dear veterinarians, I have a quick question. It looks like the cat has calcevirus. It seems to be in the early stages. According to the vet, the picture is very typical, but tomorrow we will take tests to confirm. Today we start injections anyway. The actual question is the following.

Is it dangerous to visit friends who have unvaccinated cats? Can I bring infection on clothes, shoes, or animal fur left on me? If so, how long is the virus contagious? And what can be done about this so as not to end up in social isolation, since everyone has cats, and most owners are echidnas who are too lazy to vaccinate the animals living at home.

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ru_vetfrevel

Hello!

Please tell me, dear cat breeders with sad experience of treating oncology in cats. A friend has a cat who has a cancerous tumor approximately behind the eye. The cat was taken to clinics, everything that needed was checked at the cashier. Now the question is not even that. The cat is more or less active, eats averagely, but eats, purrs, sleeps with people, goes to the litter box, etc.

He sleeps a lot, but he is also 13 years old. Dry nose. The eye looks bad, tears are flowing, it’s upside down, bulging, the cat almost doesn’t open it, but doesn’t yell or scratch it. The muzzle is deformed. How to determine that a cat is in critical pain? I heard that cats don't scream in pain like people do.

How to determine the critical point of a cat's capabilities and patience?

Ps. Tags cannot be placed from a mobile phone, moderators, sorry, I can add them in the evening.

Posted via LiveJournal app for iPhone.

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ru_vetsxizmaGood night, dear accomplices. Sorry it's so late, but I really need some advice! Friends have a cat with chronic renal failure, he is 13 years old. At the end of November, due to a chronic illness, he began to have problems with his eyes - retinal detachment.

The cat went blind in one eye, the other, having realized it in time, managed to save it - the retina, which had already detached, returned to its place - according to the doctor (and they treat the cat’s eyes at Shilkin) - a small miracle.. Now the cat is being actively treated: once a day in the morning half a tablet of Vasotope, 1/6 tablet of implodipine are given, indocollir and maxitrol are dripped into the eyes.

Also, every day he is given a daily dose in his food and every other day a subcutaneous dropper of Ringer-Locke 100 ml. This treatment continues from December 1 and must end as prescribed by a veterinarian. The last blood test was taken on January 19, the results were received yesterday and they (the results) are terrible - creatinine is over 500.

I know that with such tests, some cats fall into a coma, but their cats walk, eat, and are caressed. Questions: 1. How urgent is it to run to the doctor - now at night or wait until the morning? (you can swear because you had no luck yesterday, but it’s pointless)2.

He does not tolerate trips to the clinic well. The question is what to do with such a nervous and sensitive comrade? Is it possible not to prick his paw every day, but to put a catheter in for a few days so that he can drip at home without dragging the animal back and forth?3. There is a suspicion that a diet violation could have worsened the cat's condition.

We invite you to read: The cat asks for a cat after mating

They had already changed his food from Royal Canin kidney food to Eukanuba, they gave him pate and pieces (RK, then when he stopped eating Purina NF) - to no avail. Not far from Friday, he flatly refused to eat Eukanubu. And the cat is really not fat at all, even a little thin. Weighs three kg, the ribs can be felt. Moreover, he was always of such a frail build, from his youth - he never eroded....

In general, my friend’s mother gave the cat baby meat food so that he could eat at least a little. Is this bad-bad? Is it possible to feed him anything at all other than a renal diet, especially now, during an exacerbation? (as far as I know, no, but I need a well-reasoned opinion from a professional veterinarian - it weighs more in the eyes of the owners) THANK YOU SO MUCH in advance!

Below are scans of the tests - the last one and the earlier one, after which the medications that are now being given were prescribed.

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ru_vetaidash Hello! I can’t find a description of this behavior in any articles. Male, mongrel, 3 years old, healthy, active, uncastrated, taken from the street at the age of 3 months. During a walk, he constantly licks other people's secretions (this can be concluded, since in winter it becomes clear that what is being licked is yellow).

Moscow.

Directions for use and doses

They are set individually, taking into account the severity and localization of the infection, and the sensitivity of the pathogen.

When administered intravenously or intramuscularly for adults, the single dose is 1-1.7 mg/kg, the daily dose is 3-5 mg/kg; frequency of administration - 2-4 times/day. The course of treatment is 7-10 days. Depending on the etiology of the disease, it is possible to use a dose of 120-160 mg 1 time / day for 7-10 days or 240-280 mg once. IV infusion is carried out over 1-2 hours.

For children over 2 years of age, the daily dose of gentamicin is 3-5 mg/kg; frequency of administration - 3 times/day. Premature and newborn babies are prescribed a daily dose of 2-5 mg/kg; frequency of administration - 2 times/day; Children under 2 years of age are prescribed the same dose at a frequency of administration 3 times a day.

When applied topically, gentamicin is instilled 1-2 drops into the lower conjunctival sac of the affected eye every 1-4 hours.

For external use, apply 3-4 times a day.

Maximum daily doses:

for adults and children with intravenous or intramuscular administration - 5 mg/kg.

Pros and cons of antibiotics

There are quite a lot of positive aspects:

• pronounced broad-spectrum antimicrobial activity;
• neutralization of toxins released by microorganisms during their life processes;
• complete preservation of antibacterial properties under microorganism conditions;
• greater effectiveness in small doses;
• fast healing effect;
• relatively low toxicity when used correctly.

But behind the obvious advantages - getting rid of infection - there are also disadvantages:

• uncontrolled use of drugs causes addiction of microorganisms when antibiotics no longer work;
• many drugs are highly toxic, and an error in dosage will lead to a fatal result: severe poisoning or even death;
• frequent use with or without cause reduces the body’s overall resistance, and in the future it will not be able to independently cope with the most ordinary infectious process;
• Dysbacteriosis, which develops after taking antibiotics, should not be written off;
• allergic reactions with individual intolerance up to anaphylactic shock;
• development of side effects (we'll talk about them a little later).

For what diseases is treatment prescribed?

No matter how much you think you know exactly what the cat is sick with, self-treatment with this drug is strictly prohibited. Unless, of course, you want the cat to die in your arms. You should definitely visit a veterinarian. Moreover, you can inject Gentamicin into a cat only when it comes to gram-negative bacteria, otherwise this medication will be of no use. And it will be possible to determine the type of bacteria that are present in your cat’s body thanks to a special culture, which will be done by a specialist.

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Veterinarians attribute this medicine to the presence of many diseases, which include:

• Various respiratory tract infections.
• Problems of the urinary system, including nephritis and cystitis.
• Arthritis and arthrosis, which are provoked by the presence of pathogenic microflora in the cat’s body.
• Peritonitis, pneumonia, and other diseases that occur due to gram-negative bacteria.

And remember, injecting a cat with Gentamicin is not an easy task at all, since injections of such a drug are very painful. Therefore, the animal must be held very tightly. To carry out this procedure, you should take an assistant or use a special retaining bag.

Indications

injection solution is clinically effective against infections caused by sensitive gram-negative and gram-positive bacteria

, including Pseudomonas aeruginosa, indole-negative and indole-positive Proteus species, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Arizona hinshawii and Staphylococcus. The use of gentamicin solution is indicated for the treatment of infections caused by susceptible bacteria determined in the laboratory, taking into account the relative toxicity of antibiotics. Therefore, the drug should be considered as follows:

• Urinary tract infections (cystitis and nephritis)
• Bacteremia/sepsis
• Infected wounds
• Soft tissue infections
• Respiratory tract infections
• Gastrointestinal infections
• Escherichiosis
• Uterine infections

Metritis and cervicitis in horses associated with bacteria such as E. coli, S. aureus and Streptococcus species that are sensitive to gentamicin.

The method of treating metritis in cows associated with systemic lesions should be at the discretion of the treating veterinarian.

As an aid in preventing mortality in the first two weeks of life in 1- to 3-day-old turkey poults caused by Chinshawia infections in Arizona.

Prevention of early mortality in birds caused by E. coli, Salmonella typhimurium and Pseudomonas aeruginosa, sensitive to gentamicin.

In most cases, bacteriological cultures must be obtained initially to identify the pathogen and determine its sensitivity to gentamicin injection solution. Discs with a sensitivity of 10 µg are available for this purpose.

Gentamicin injection solution should also be considered for staphylococcal infections when other conventional antimicrobial therapy is not appropriate or when bacterial susceptibility testing and clinical judgment indicate its use. If susceptibility tests indicate that the pathogen is resistant to gentamicin, other antimicrobial therapy should be initiated.

Main characteristics of the drug

Belongs to the group of aminoglycoside antibiotics and is considered one of the oldest drugs used both in veterinary medicine and in medicine. It only acts (!) on gram-negative bacteria (that is, the drug does not have a broad spectrum of action); it is effective against gram-positive microorganisms in very rare cases. Therefore, before using gentamicin, it is necessary to do cultures and accurately determine the species of the pathogen in each specific case. Otherwise, you will endanger the life and health of your cat by unnecessarily feeding him an antibiotic that is far from safe.

By the way, regarding safety. On veterinary forums you can often find information that it is not worth treating cats with gentamicin. There are frequent cases of problems with the ears and kidneys. There is indeed some truth in this point of view. The problem is that this drug has ototoxic and nephrotoxic effects. Simply put, it hits the ears and kidneys. So you need to be careful when injecting gentamicin into your cat. Under no circumstances should you use this medicine on your own, “for prevention”! There is a high probability that you will simply destroy your pet or, at least, make it disabled.

But this only applies to cases of overdose and too long a prescription. If you administer the drug strictly according to the instructions, without exceeding the recommended dose and duration of treatment, then everything will be fine. Of course, you need to remember about the possibility of individual intolerance to gentamicin by your cat. If the injections have somehow negatively affected the animal’s behavior, or if something else bothers you, call a veterinarian immediately.

Important! Injections of this drug are highly painful, so the animal must be held tightly during all manipulations.

Overview of Gentocin® in Cats

Gentamicin, also known as Gentocin® and Garamycin®,

is an antibiotic that inhibits bacterial growth by inhibiting protein synthesis. Thanks to this mechanism, gentamicin quickly kills bacteria in cats.

According to the instructions for use, gentamicin belongs to a special class of drugs - aminoglycosides.

Other related drugs in this pharmacological class include neomycin, amikacin, tobramycin, and kanamycin.

According to the instructions for use, gentamicin is effective against a wide range of bacteria in cats. It is effective against bacteria that affect the circulatory system, respiratory tract, skin, body cavities, sinuses, ear canal and bladder.

Gentamicin is a prescription drug and can only be obtained from a veterinarian or as directed by a veterinarian.

Gentamicin is available to veterinary clinics in the form of injections and topical applications (such as ointments and drops for skin or eye infections).

Purpose and possible restrictions

Polyarthritis in an animal is one of the indications for prescribing this drug.
Injections with Gentamicin solution are indicated for cats and female cats in which the following pathological conditions were identified during a diagnostic examination:

• dermatitis;
• respiratory diseases;
• nonspecific infectious inflammatory kidney disease;
• polyarthritis, arthritis;
• diffuse inflammation of the peritoneum;
• sepsis;
• gastrointestinal infections.

However, it is not always permissible to inject Gentamicin into a cat. The medication is strictly contraindicated if the pet has an individual intolerance to its components. In addition, the medicine cannot be administered if the purr is simultaneously being treated with cephalosporins, Polymyxin, penicillins, Colistin and other aminoglycoside antibiotics. The medication is also contraindicated for newborn kittens, pregnant and lactating individuals, as well as pets with impaired renal function.

Treating a cat's cold with antibiotics

When a person gets a cold, this is a common occurrence, but when a cat catches the virus, we are often lost and don’t know what to do. After all, our pets are not able to tell us that they feel bad and where it hurts. So what should you do if your cat gets a cold? Run to the clinic or try to cure it at home. What are the best antibiotics for cats to buy for colds? We will try to answer these and other burning questions for you today.

We have already described the symptoms of colds in cats many times, so let's just list them:

• Dry nose;
• Apathy;
• Loss of appetite;
• Discharge from the nose and eyes;
• Sneezing and coughing.

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If you notice these symptoms, you should go to the hospital. If an animal gets sick during the cold season, it is better not to risk it and call a doctor at home. Such a walk can only complicate the situation. After the examination, the doctor will make an accurate diagnosis and, depending on the severity of the disease, the veterinarian may prescribe an antibiotic.